Technology
NCE
The proprietary molecules of Affichem are New Chemical Entities (NCE) discovered while studying the mechanism of action of Tamoxifen.
These molecules are inducers of cell differentiation.
Depending on the subfamily to which they belong, these molecules induce cancer cells redifferentiation and death (AF122) or cause neuronal differentiation and the survival of neurons (AF243).
Due to their effects, these molecules enable damaged cells or cells perturbed by a disease, a trauma or age, either to recover a normal activity or to be eliminated.
Moreover, their production by chemical synthesis is simple and without the risk of biological contamination.