The proprietary molecules of Affichem are natural New Chemical Entities (NCE) discovered while studying the mechanism of action of Tamoxifen in INSERM lab of Dr Marc POIROT.
These molecules are strong inducers of cell differentiation.  

Due to their effects, these molecules enable damaged cells or cells perturbed by a disease, a trauma or age, either to recover a normal activity or to be eliminated. 

Depending on the subfamily to which they belong, these molecules induce cancer cells redifferentiation and death (AF122) or cause neuronal differentiation and the survival of neurons (AF243) or stimulate melanin production in skin (AF130).

Moreover, their production by chemical synthesis is simple and without the risk of biological contamination.

 
Cancer - Melanoma - Deafness - Neurodegenerative disease - Drug design - Anticancer therapy - Cell differentiation - Receptor - Enzyme - Metabolism - Medicinal chemistry - Biotechnology - First in class molecule - New Chemical Entities - Cholesterol - Tamoxifen - Immunotherapy - Exosome - Oncology - Dendritic cell -