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11 documents found for "Cancer"

1. Cancer

... market in Europe and in the United States. AF122 has a dual mechanism of action, acting directly on cancer cells but also on immune system. Indeed, AF122 induces cell differentiation followed by active ...

2. Affichem USA Inc.

... Dr. Marc Poirot and Dr. Sandrine Silvente-Poirot (Affichem co-founders) as leaders in field of cancer and cholesterol metabolism. The discovery of Dendrogenins and their unique biological properties ...

3. Predictive & Monitoring Biomarker

... AF300. Affichem is developing a biomarker to improve the care of breast cancer. Breast cancer is the most widespread cancer in women, representing 1.4M new cases per year and death. Breast ...

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4. Links

http://www.inserm.fr/ http://www.claudiusregaud.fr/ http://www.eurohear.org/ http://cordis.europa.eu/fp6/dc/index.cfm?fuseaction=UserSite.FP6HomePage http://www.inserm-transfert.fr/ http://www.oseo.fr/ http://www.cancerbiosante.fr/ http://www.incubateurmipy.com/ http://www.midipyrenees.fr/ http://www.enseignementsup-recherche.gouv.fr/ http://www.grandtoulouse.org/ http://www.sigmaaldrich.com/ http://www.spibio.com/ ...

5. Publications

... antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism. Mol Cancer Ther, 7(12):3707-18, 2008. de ...

6. Biomarkers

... of a biomarker for cancer detection and monitoring the efficacy of anti-cancer drugs : AF300.  As a result of metabolomic ...

7. AF122

... T lymphocytes, makes AF122 an anti-tumour agent that represents a technological breakthrough for cancer ...

8. NCE

... or to be eliminated.  Depending on the subfamily to which they belong, these molecules induce cancer cells redifferentiation and death (AF122) or cause neuronal differentiation and the survival of ...

9. Scientific Advisory Board

... level experts in the therapeutic fields of Affichem. M. Poirot PhD, Research Director of INSERM, Cancer Research Center of Toulouse (France) - Chairman Cancer S. Silvente-Poirot PhD, Research Director of ...

10. Management

... head of the unit “Sterol metabolism and therapeutic innovations in oncology” (UMR 1037 CRCT - Cancer Research Center in Toulouse, France). He has a PhD in Chemical Biology, followed by a three years ...

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Biomarker - Drug design - Anticancer therapy - Cell differentiation - Receptor - Enzyme - Metabolism - Cancer - Deafness - Melanoma - Neurodegenerative disease - Medicinal chemistry - Biotechnology - First in class molecule - New Chemical Entities - Cholesterol - Tamoxifen - Immunotherapy - Exosome - Oncology - Dendritic cell - Theranostic - Diagnosis - Prognosis -